Nevertheless, creating accurate and visually appealing representations of gene neighborhoods is frequently required. Except for genome selection and region window size, the display parameters are precomputed and fixed, and manipulation and export of representative image is impossible. Most of the specialized databases such as SEED ( Overbeek et al., 2005), Integrated Microbial Genomes ( Markowitz et al., 2012), Pathosystems Resource Integration Center (PATRIC) ( Wattam et al., 2017), MicroScope ( Vallenet et al., 2009) and Search Tool for the Retrieval of Interacting Genes/Proteins ( Snel et al., 2000) allow users to display genes of interest and their neighbors. Thus, displaying and collating gene clusters is a common step in comparative genomics. Conserved physical clustering of genes (conserved genome context) in phylogenetically distant genomes is a strong suggestion of functional association ( Overbeek et al., 1999).
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